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Doctors split on new report that sleeping pills can increase risk of brain cancer (2015/04/30) Long-term use of a common sleep medication can increase the risk of brain cancer by 98 percent. That’s the conclusion of a study done by Taiwan’s College of Medical Science and Technology. But some doctors are not completely convinced. Taiwanese take an average of 320 million sleeping pills a year. A new report says that long-term use of sleeping pills can increase the risk of several kinds of cancer, especially brain cancer. Jack Li Dean, Medical Science and Technology College Whether in animal trials or in epidemiological surveys like this, we have found that sleeping pills can affect the risk of specific cancers. Jack Li’s team analyzed health insurance records in Taiwan from 1998 to 2011 and found that usage of the most common form of sleep medication – benzodiazepines or BZD – increased the risk of brain cancer by 98 percent. Jack Li Dean, Medical Science and Technology College The principle behind BZD is that it enhances the actions of an inhibitory neurotransmitter called GABA. It can cause cells to develop in different ways or along different paths. Some doctors are not sold on the findings. Yeh Chin-bin Tri-Service General Hospital Psychiatrist Actually in this kind of study, it did not account for risk factors like smoking, drinking or even daily habits. This is something that has to be understood. Medical experts are urging patients with sleeping disorders to discuss this with their doctors. They also advise against unauthorized use or increased use of sleeping pills to prevent further harm to one’s health.

中文 Chinese

最新研究安眠藥增腦癌風險 醫界看法不一

台灣安眠藥濫用問題嚴重，台北醫學大學最新研究發現，長期吃含有"苯二氮平"類的安眠藥，腦癌風險暴增98%，論文還登上國際期刊。但也有醫生持保留態度，認為只憑數據分析太過武斷！

台灣人平均一年就吃掉3.2億顆安眠藥，但最新研究發現，長期吃，恐怕增加罹癌風險。

[[北醫醫學科技學院院長 李友專]]
“不管是在動物實驗，或是像我們這樣流行病學調查，都發現說安眠藥，會對特定癌症風險會改變”

北醫分析1998-2011年健保庫資料，得出最多病患使用的苯二氮平類（BZD）安眠鎮靜劑，罹患腦癌風險高達9成8。

[[北醫醫學科技學院院長 李友專]]
“苯二氮平類它的原理，它是抑制一個腦神經傳導物質"GABA"，可能影響到細胞其他的發展或其他路徑”

但醫界也有質疑聲浪。

[[三總兒少精神科主任 葉啟斌]]
“其實在這樣的研究中，並沒有去囊括有抽菸、喝酒，甚至是平常生活習慣這些危險因子，這是必須要再去了解的”

醫界呼籲，失眠患者最好先跟醫生充分討論，更別擅自服用或加量，免得造成更嚴重的傷害。